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[9002098.] رقم البحث : 9002098 - |
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Multidisciplinary Management of Spinal Chordoma: Single Institution Study / |
| تخصص البحث : General |
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SECI Oncology Journal / |
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هشام حمزه - مؤلف رئيسي |
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Spinal Chordoma ,bone neoplasm ,surgical treatment |
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Introduction: Chordoma are rare, slowly growing, locally aggressive neoplasms of bone that arise from embryonic remnants of the notochord. This work aimed to evaluate the treatment results of a series of chordoma patients in our institute. More also, we try to clarify the importance of approaching such patients through a multidisciplinary team to maximize the oncologic and functional outcomes and to improve the patient’s quality of life. Patients and Methods: This study was conducted at SECI, surgical department during a period of 6 years duration. Patients were treated through multi-disciplinary team specialists of our cancer institute. Surgery and postoperative radiation therapy was offered to all patients. Results: Results involves 8 patients with an average follow-up interval of 38.5 months. We had four cases of local recurrence which was salvaged with re-surgery and/or adjuvant radiotherapy. We had no postoperative motor neurologic deficit, with an excellent sphincter control in all patients. The 3-year survival rate in this study is 87.5%. Conclusions: Multi-disciplinary treatment approach for chordoma is fundamental to improve overall outcomes. Surgery continues to be the primary modality in the management of chordoma. Rates of local recurrence, as well as survival, appear to be dependent on the achievement of negative surgical margins. Patients who relapse locally may have a poor prognosis but both radiation and surgery can be used as salvage therapy. |
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