الفهرس | Only 14 pages are availabe for public view |
Abstract iver Cirrhosis is widely prevalent worldwide and can be a consequence of different causes, such as obesity, non-alcoholic fatty liver disease, high alcohol consumption, hepatitis B or C infection, autoimmune diseases, cholestatic diseases, and iron or copper overload. Cirrhosis develops after a long period of liver inflammation that results in replacement of the healthyodules, with fibrotic tissue and regenerative n parenchyma. The disease evolves from an portal hypertension leading toasymptomatic phase (compensated cirrhosis) to a symptomatic phase (decompensated cirrhosis), the complications of which often result in hospitalisation, impaired quality of life, and high mortality (Ginès et al., 2021). The aim of the present study is to asses effect of serum lactate, Unmeasured anions and Chloride as predictors to the outcome of critically ill patients with liver cirrhosis. This study was conducted on 95 patients divided to 4 groups according type of metabolic acidosis (lactic acidosis group, unmeasured anions acidosis group , hyperchloremic acidosis group, indeterminate acidosis group). This present study showed strong significance between (lactic acidosis), (unmeasured anion acidosis) and mortality incidence when compared with APACHE II score on day 0 (admission day). where as HA was not related to mortality prediction, and alterations in [Cl–] corrected were not independently Conclusion 115 related to outcome hyperchloremia (hyperchloremic acidosis) was independently related to outcome . The main finding in this study ,also , was that lactic acidosis constituted the most common type of metabolic acidosis incidence at admission |