الفهرس 
Title : Changes in red cell distribution width during hospitalization and its prognostic value in patients with acute heart failure with impaired left ventricular systolic function
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Abstract
Background: Increased red blood cell distribution width (RDW) is associated with adverse outcomes in heart failure. In the present study, we assessed the association between baseline and changes in RDW values during hospitalization and short-term prognosis in patients with acute heart failure (AHF). Methods: We measured the RDW value in 250 consecutive patients with AHF. Blood samples were obtained at the time of hospital admission (RDWadm), weekly and within 24 hours before discharge. {u2206}RDW was defined as the last RDW within 24 h prior to discharge minus the first RDW. Patients were followed up for 30-day post discharge. Results: Higher values of RDWadm and {u2206}RDW were associated with worse NYHA functional class and clinical status on admission and discharge respectively. Higher values of RDWadm were associated with the development of renal impairment, arrhythmia, cardio-genic shock and death, and with prolonged length of hospital stay and lower left ventricular ejection fraction. While higher values of {u2206}RDW were associated with the development of cardiogenic shock and death. Both higher RDWadm and {u2206}RDW were associated with 30-day mortality and readmission (all P<0.05)