الفهرس 
IDIOPATHIC PULMONARY FIBROSISOnly 14 pages are availabe for public view
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Abstract
SUMMARY
Patients with IPF exhibit characteristic features regarding the respiratory and cardiac muscle function. The lack of an association between diaphragmatic mobility and echocardiography findings of right and left ventricle functions in patients with IPF was unexpected as transthoracic US and echocardiography are feasible, reproducible, noninvasive, and largely adopted in the clinical practice and in clinical trials.
A prospective case–control study was conducted in which 40 patients with IPF and 10 controls underwent transthoracic US assessment of diaphragmatic excursion and echocardiography study to correlate between diaphragmatic mobility and ventricular functions in patients with IPF, and the study revealed the following:
The deep breathing excursion mean was statistically significant decreased among the study group in comparison with the control group as it was 4.09 and 6.44 cm among the study and control groups respectively.
RVFAC, TAPSE, and EF means were statistically significant decreased among the study group in comparison with the control group as mean RVFAC was 44.03% and 49.0%, mean TAPSE was 19.60 mm and 21.20 mm, and mean EF was 63.05% and 67.5%, among study and control groups respectively.
PASP mean was statistically significant increased among the study group (46.90 mmHg) in comparison with the control group (20.1 mmHg).
Both normal breathing excursion and deep breathing excursion have positive correlation with RVFAC and TAPSE in both study and control groups.