الفهرس 
Technique and Practical Points in the Interpretation of PET/CT ScansOnly 14 pages are availabe for public view
 |  | from | 118 |  |  |
| | | from | 118 | | |
Abstract
Abstract
Background: Fever of unknown origin (FUO) is a challenging clinical problem in medicine that needs collaboration of various diagnostic techniques to establish the accurate diagnosis. We evaluated the diagnostic performance of 18F-FDG PET/CT in patients who presented themselves with fever of unknown origin (FUO). Our study included 40 patients with FUO who underwent PET/CT examination and their results were compared to the results of laboratory, histopathological, microbiological investigations and / or response to therapy.
Results: The final diagnosis included malignancy in 20 patients (50%), infectious causes in 7 patients (17.5 %) and non-infectious inflammatory causes (NIID) in 6 patients (15 %). Fever resolved without diagnosis in 4 patients (10 %) while no definite diagnosis was reached in 3 patients (7 %). PET/CT successfully contributed to diagnosis of 35 out of 40 patients with diagnostic accuracy of 87.5 %. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of PET/CT in our study were 93.5 % ,66.7 %, 90.6 % and 75 % respectively.
Conclusion: PET/CT is a useful tool to investigate and diagnose the cause of FUO. It provides information that can guide the treatment strategy of the patients.