الفهرس 
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Abstract
ABSTRACT:
The aim of this study is to assesse the ideal level of iron : zinc fortification according to their absorption. Methods: Fifty six weanling male albino rats of Sprague-Dawley strain weighing (40±5gm) aged 30 days were subjected, the rats divided into three main groups. The first group fed on basal diet (control), and the second group (Iron group) divided into three subgroups which fed on different doses 2 , 5 and 10 fold RDAs of Fe: 1 zinc as Feso4 (Ferrous sulfate hydrate, 55.845% Fe, Food grade), and the thired group (Zn group) fed on different doses 2, 5 and 10 folds RDA of Zn : 1 Fe as Znso4 (Zinc sulfate, 7H2O, 65.409% Zn) ingredient annular for 8 weeks. Histopsthological changes in liver and spleen were investigated. Results: Fortified. with 2 fold RDA of iron has a significant increment (P≤ 0.05) in food intake, body weight gain and feed effeciency. While significant decrements were documented for 10 fold RDA of iron and 2,5and 10 fold RDA of zinc groups. Relative weight of liver increased significantly (P≤ 0.05) in groups 5 and 10 fold for both iron and zinc, there were a significant increments in all fortified groups . Also Haemoglobin increased significantly (P≤ 0.05) in 2 and 5 fold RDA of iron groups, whereas decreased significantly (P≤ 0.05) in all groups of zinc, the heighest level of iron and zinc fortifiecation decreased RBCs and WBCs and total iron significantly (P ≤ 0.05). All levels of fortificat increased significantly ( P ≤ 0.05), the total iron binding capacity except levels (5 &10) of zinc fortified, which significantly decreased ( P ≤ 0.05). Whereas, zinc plasma increased significantly ( P≤ 0.05) as much as level of zinc suppllementation. All groups of supplementation increased significantly ( P≤ 0.05) in serum ferritin and decreased significantly ( P≤ 0.05) in Cu-Zn superoxide dismutase enzym. In conclusion, heighest level of zinc suppllementation decreased total iron and its binding capacity.