الفهرس 
Haemostasis and Blood CoagulationOnly 14 pages are availabe for public view
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Abstract
Coagulopathies in ICU are one of the most common complications in ICU. DIC is one of the most threatening coagulopathies in ICU .It is accompanied with high mortality rates in ICU.
Early diagnosis of DIC is very important for early intervention for better prognosis.
DIC is caused by several pathologies like sepsis, trauma, obstetric causes and malignancies.
DIC has many predictors and measures and can’t be diagnosed by single laboratory test. So DIC scoring systems are used for better diagnosis like ISTH and JAAM scoring systems.
Laboratory tests used in DIC includes many tests but lack sensitivity and specificity, so a new parameter in a recent study was suggested Fibrinogen/CRP ratio with odds ratio 6.15 compared to fibrinogen only.
In this study, Fibrinogen/CRP ratio showed more sensitivity than fibrinogen alone.
In our study, we compared this new parameter versus classical parameters of diagnosis of DIC which are D-dimer and FDPs.
It was conducted on 70 patients in Demerdash ICU after including patients with ISTH score ≥5; 2 samples were collected from each patient.
First group of samples was used for analyzing Fibrinogen and CRP ratio was done and low ratio was used as a positive result.
Second group of samples was used for analyzing D-dimer and FDPs and positive values were calculated and tabulated.
In our study, the results were in favor to the classical parameters of diagnosis of overt DIC in comparison to the new parameter of DIC.
It showed that D-dimer and FDPs together were more sensitive than fibrinogen/CRP ratio.