الفهرس 
Chronic Obstructive Pulmonary Disease (COPD)
Smoking burden in EgyptOnly 14 pages are availabe for public view
 |  | from | 150 |  |  |
| | | from | 150 | | |
Abstract
Malnutrition, weight loss, and peripheral muscle
weakness are some of the systemic manifestations of
COPD that seriously affect the health related quality of life
and exercise capacity of patients (Decramer et al., 2005).
The BODE index components are: body mass index (BMI),
airway obstruction (O), dyspnea (D) and exercise capacity
(E) (Celli et al., 2004). The COPD Assessment Test (CAT)
is a quick and easy test to be completed and provides a
score that indicates the impact of the disease on the health
status of the patients (Gu et al., 2014).The aim of this study
was the assessment of the quality of life in COPD patients
using CAT and correlating with BODE index.
COPD patients in this study were diagnosed and
classified into four groups according to GOLD guidelines.
BODE index score was calculated according to: BMI,
FEV1%pred. post bronchodilator, mMRC and 6MWT
(meters) by summing the points that were obtained. CAT
questionnaire was used to assess the quality of life. Total
CAT score and BODE index score were calculated and data
analysed using various statistical tests.
In the current study, 60 COPD patients were
investigated. Among these, the mean age of the patients
were 63.383 ± 10.306 (40 - 87) and the sex ratio (M: F) was (58:2). The majority of the studied cases were Ex-smokers
and only 3.33% were passive smokers. Mean BMI (kg/m2)
was 25.338 ± 4.810, mean FEV1% pred. postbronchodilator
was 40.433 ± 9.464, mean mMRC was 1.8 ±
0.9 and mean 6 MWT (m) 204.900 ± 83.926. In this study,
mean BODE Index Score was 6.067 ± 1.745 and mean total
CAT Score was 27.967 ± 7.746. BODE Index and CAT
Score was found to be highly significantly related to the
disease severity according to GOLD (p<0.001). The BODE
Index was positively correlated with CAT score (r = 0.986).
This correlation was found to be statistically highly
significant (p < 0.001).