الفهرس 
Movement Disorders: An Overview
Anatomy of Basal GangliaOnly 14 pages are availabe for public view
 |  | from | 195 |  |  |
| | | from | 195 | | |
Abstract
Background:
Dystonia is the third most common movement disorder after tremors and Parkinson‟s disease, that significantly renders the functionality of an individual and hence the society. Our aim is to clinically assess the role of bilateral pallidotomy on twelve patients with generalized dystonia.
Method:
This study is done on a retrospective manner on twelve patients (6 males- 6 females), with age range from (8-29) with heterogenous etiologies of generalized dystonia, who received Bilateral posteroventral Pallidotomy, aiming to lessen the severity of the dystonia. Guided by a peri-operative clinical assessment and scaling with Burke–Fahn–Marsden dystonia rating scale. All patients had a post operative MRI to confirm pallidotomy lesion site.
Results:
All had a noticeable improvement on BFM score and the severity of the dystonia after one month follow up, but for one patient who had an associated contracture and scoliosis that rendered his clinical improvement where the BFM score mean pre-operative 62.2, while post operative BFM score mean was 36.5 (p value= 0.001) , thus there is a 41.4% reduction in the mean BFM score.
Conclusion:
Bilateral posteroventral Pallidotomy is considered a safe and effective line of management in generalized dystonia. None the less it doesn‟t carry the drawbacks of other alternative managements as in DBS, like hardware hazards, from infection or dislocation, or its long term maintenance and high costs. By highlighting the efficacy of pallidotomy and studying more patients and with applying our data to more comparative studies, that will lead us to more understanding to the most suitable option for each patient.
Key words: Pallidotomy, Dystonia, Posterolateroventral.