Search In this Thesis
   Search In this Thesis  
العنوان
THE RELATIONSHIP BETWEEN ENVIRONMENTAL
STRESSORS AND PSYCHIATRIC CO-MORBIDITY TO
CLINICAL PROFILE AND SEVERITY OF PSORIASIS /
المؤلف
Fawzy,Azza Mahmoud Ismail.
هيئة الاعداد
باحث / Azza Mahmoud Ismail Fawzy
مشرف / Ehab Mohamed Eid
مشرف / Wafaa Afifi Mahmoud Hammad
مشرف / Mostafa Hassan Ragab
تاريخ النشر
2017
عدد الصفحات
211p.:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصحة وعلم السموم والطفرات
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - معهد البيئة - العلوم الطبية البيئية
الفهرس
Only 14 pages are availabe for public view

from 211

from 211

Abstract

Psoriasis is connected with higher rates of depression and anxiety, and
people with severe psoriasis die, on average, four years younger than people
without the disease. The impact of psoriasis on patients’ overall quality of life
is significant, broad, and deep, including effects on emotional well-being,
psychological stress, self-esteem, relationship, work, social activities,
financial burden, and even physical function.
Psoriasis occurs worldwide and has no gender preference; however, its
prevalence and incidence estimates show ethnic and geographic variations,
being generally more common in the colder north than in the tropics. A
performed systematic review of published population-based studies on the
incidence and prevalence of psoriasis and concluded that the prevalence in
children ranged from 0% (Taiwan) to 2.1% (Italy), and in adults it varied from
0.91% (United States) to 8.5% (Norway).
Many environmental factors have been linked to psoriasis, and have
been implicated in, such as disease process initiation or exacerbation.
However, conclusive evidence is so far lacking. Environmental risk factors
include; trauma, infections, drugs, sunlight, the 3-month postpartum period,
stress, seasonal variation, and smoking and alcohol.
The relationship between stress and psoriasis is likely more complicated.
A significant association of psychiatric morbidities in psoriasis was recorded
in 25 (50%) in psoriatic patients. The proportion of major depressive
disorders (MDD) was among psoriasis patients 15 (30.0%). However, patients
in terms of anxiety disorders were 8% in psoriasis. In patients with psoriasis,
MDD was found highest (30.0%) followed by anxiety disorders (8.0%),adjustment disorder (4.0%) and somatoform disorder not otherwise specified
(2.0%).
The impact of psoriasis on patients’ overall QoL is broad and deep,
including effects on emotional wellbeing, psychological stress, self-esteem,
relationships, work, social activities, financial burden, and even physical
function (particularly in patients with coexistent psoriasis arthritis).
Aims of the study were identify patients with their various clinical
profile and severity, investigate the types of stressors, the types of quality of
life, the types of psychosocial factors, and studying the correlation between
the co-morbid psychiatric disorders and the forms and severity of clinical
profile of psoriasis.
Subjects and Method:
Subjects: 150 patients were collected from dermatological out-patient
clinic affiliated to ministry of health and universities hospitals. Quality of life
will be assessed for them.
Procedures: 1. Socioeconomic data were collected for all patients. 2. A
full dermatological history was taken including; exacerbating factors. 3. All
patients completed the Holms and Rahe for assessment of stressors. 4. All
cases of psoriasis were examined generally to exclude chronic diseases. 5. All
patients were subjected to complete clinical examinations. 6. Psoriasis area
severity index were measured on a scale of 0 to 4 from none to maximum. 7.
All patients completed the self-rated long form of MINI (Mini International
Neuropsychiatric Interview). 8. All patients were assessed for dermatological
life quality index.