الفهرس 
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Abstract
Delirium is a common clinical syndrome in ICU it is characterised by disturbed consciousness, cognitive function or perception, which has an acute onset and fluctuating course. It is a serious condition that is associated with poor outcomes. However, it can be prevented and treated if dealt with urgently.
Delirium has received little attention in intensive care because it is- expected to be an outcome of intensive care, or is believed to have no adverse consequences in terms of the patient’s ultimate outcome.
Screening critically ill patients using Confusion Assessment Method for the ICU (CAM- ICU) is a valuable method in diagnosis of delirium specially in intubated patients. Other diagnostic instruments for ICU delirium have been developed, but the only one that has reached widespread use is the Intensive Care Delirium Screening Checklist (ICDSC).
Antipsychotics are the cornerstone of pharmacological treatment and have been shown to be effective in treating symptoms of both hyperactive and hypoactive delirium.
Haloperidol can be administered by intravenous, intramuscular or oral routes, it remains the first-line treatment in many clinical guidelines. Potential benefits of atypical compared with typical antipsychotics include the lower propensity to cause over-sedation and extrapyramidal adverse effects. Most atypical antipsychotics are only available as an oral formulation (except olanzapine which is available in intramuscular formulation), which restricts their use in patients in whom oral intake is not possible.In the present study we aimed-to evaluate the use of Olanzapine in the treatment of delirium in ICU, as regard its efficacy and safety profile compared to Haloperidol.
We compared our present study by other studies carried to compare between Olanzapine and Haloperidol in-treatment of delirium in ICU. Most results matched with our present results and some not matched with.
The results of the present study showed that both drugs are equally effective in treatment of delirium in ICU and their safety profile is the-nearly the same.