الفهرس 
Introduction and Aim of workOnly 14 pages are availabe for public view
 |  | from | 349 |  |  |
| | | from | 349 | | |
Abstract
Abnormal cerebral haemodynamics seems to be a significant cause of morbidity and mortality in ventilated preterm infants. However ,our understanding of the CBF among the neonatal age group remains relatively unclear, and still relies relatively on data obtained from studies done on animals or adults.The present work was planed to clarify the hemodynamic changes in regional CBFV in preterm infants receiving different respiratory support modalities at the time of ideal ventilation. In addition, we tried to clarify the effect of different therapeutic modalities and different complications of prematurity on CBFVs. This study was carried out on 56 preterm infants; who were admitted NICU (MUCH) in the first 12 hrs of their life, in the period from March 2005 to April 2006 due to the presence of respiratory distress, diagnosed as RDS.Cranial Doppler was done for all subjects and control in day 1 and day 4 with measurements of PSV, EDV, MV, RI and PI) in the ACA and MCA. In day 1, they were 56 P and in day 4, they were reduced to 37. Echocardiography was done for the same infants at the same time to assess the presence or absence of PDA. The results of our study: there was significant decrease of MV in the ACA and EDV and MV in MCA in HFOV group when compared with control group and no significant differences between other groups and control as regard cerebral haemodynamics in the 1st day of life and there were significant decrease of EDV and MV in MCA in HFOV group when compared with control group, in the 4th day of life. from our study we conclude that: HFOV decrease CBF in both 1st and 4th day of life when compared with control and CMV groups despite of no differences in variables which may affect CBF.