الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Ovarian stimulation by gonadotropins induces a rise in stromal blood flow velocity as evidenced by two-dimensional color Doppler studies. The rise in stromal blood flow velocity is associated with a concurrent increase in serum vascular endothelial growth factor (VEGF) concentration. The VEGF or HIF (Hypoxia Induced Factor) is an endothelial cell mitogen with potent angiogenic properties leading to splitting, budding and branching and expansion of vessel walls, in regions of endothelial tips that show maximum sensitivity. Serum VEGF levels have a positive correlation with perifollicular blood flow. This can be easily measured by two-dimensional Color and Pulsed Doppler ultrasonography. Uterine artery Doppler analysis has the potential to predict pregnancy complications associated with uteroplacental insufficiency before the onset of clinical features. Color flow Doppler is applied and the uterine artery is identified at the level of the cervicocorporeal junction. Measurements are taken at this point before the uterine artery branches into the arcuate arteries. The decreased UtAPI, particularly during the luteal phase, together with the increased blood velocity in the UtA and its vascular network, indicated increased uterine perfusion in preparation for implantation. In fact, low PI of the uterine artery and endometrial flow were associated with improved implantation rates, further supporting the view that increased local perfusion favours successful establishment of pregnancy. The aim of this study to evaluate the role of uterine artery Doppler indices in the second half of stimulated cycle as predicator of early pregnancy occurrence. This study was a cross sectional study which was conducted among eighty infertile women (80) who were treated by stimulant drugs for ovulation induction and were presented to outpatient clinic and of Obstetrics and Gynecology of both Tanta University Hospital and Damanhour medical national institute during period from 2022 and fulfillment of all cases. The results of our study showed that the basic demographic and clinical data including age, BMI, menstrual regulation and infertility period shows insignificant difference between pregnant and non pregnant group, this results was important to eliminate the effect of demographic and clinical data on out come of the study. Regarding uterine artery measurements, it was found that the left and right PI and RI showed insignificant difference in the two studied groups (pregnant and non pregnant).