الفهرس 
COMMUNITY ACQUIRED PNEUMONIAOnly 14 pages are availabe for public view
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Abstract
admission, interventions needed in management, need for surgical intervention And Outcome.2.Thorough clinical examination laying stress on: Local chest examination. 3. Laboratory Investigations: CBC with differential, CRP and Microbiological Cultures. 4. Radiological investigations to confirm the diagnosis and determine the presence of complications or not: Chest X Ray, CT Chest (in complicated CAP patients) and Chest ultrasound.
Results: Serum TRAIL level was significantly higher in CAP patients than healthy controls with median (IOR)= 469.95 (323.9 - 743) ng/l and 41.44 (30.98 -51.16) ng/l respectively. Serum TRAIL level was significantly higher in complicated CAP patients than in uncomplicated CAP patients with median (IOR)= 743 (602–981.9) ng/l and 323.9 (236.3–422.6) ng/l respectively. second hand smoking(passive exposure to cigarette smoke) was significantly higher in complicated CAP patients than in uncomplicated CAP and healthy controls (P=0.023). Shorter duration of breast feeding was significantly higher in complicated CAP patients than in uncomplicated CAP and healthy controls (P=0.001). complicated and uncomplicated CAP patients were generally under-weight with median (IQR) Z score for weight 0 (-1 – 0) in complicated CAP and -1 (-2 – 0) for uncomplicated CAP. The duration of symptoms before hospitalization was significantly longer in complicated CAP patients than uncomplicated CAP patients with median (IOR)= 10 (7-15) days and 4 (2-7) days respectively. The duration of hospital admission was significantly longer in complicated CAP patients than uncomplicated CAP patients with median (IOR)= 21.5 (16-30) days and 7 (5-9) days respectively.the outcome of all patients was improvement with no mortality.
Conclusion: Serum TRAIL is statistically significant higher in complicated CAP patients compared to uncomplicated CAP patients; hence it can be regarded as biomarker for severity and complications among CAP children.