الفهرس 
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Abstract
E
ndometrial cancer (EC) is the most common gynecological neoplasm of female genital organ in developed countries accounting for 50% of all gynecological cancer. The imaging routine in preoperative assessment of EC differs amongst the gynecologists. The advantages of cross-sectional imaging are taken for granted in computed tomography and magnetic resonance imaging. Recently, tomographic ultrasound has introduced these advantages to sonographic volume imaging.
The development of increasingly sophisticated computer hardware and software tools has advanced to the point that computed tomography- and magnetic resonance imaging (MRI)-like technologies are now incorporated into ultrasonography systems. These new technologies permit, among other things, use of the entire 3D US data set to create a cube that can be sliced and displayed in various ways using intuitive interfaces and the resulting data can be extracted along a flat plane.
The aim of the study: was to evaluate the potential accuracy of 3D tamographic ultrasound imaging (TUI) coupled with power Doppler in comparison to computed tomography scan in the detection of depth of myometrial invasion and stromal invasion in endometrial cancer in relation to histopathology.
The study was cross-sectional study (Diagnostic purpose) included fifty biopsied women who are pathologically proven endometrial cancer for two years (December 2018-December 2020). This study conducted at Ain Shams university Maternity Hospital (Gynecology oncology unit)
To fulfill the objectives of the study the researcher, based on the recent national and international guidelines related works of literature to collect the necessary study data following these procedure steps:
All the study participants were subjected to the following:
1. History taking including
Personal history
Past medical surgical history
Drug History
Family History
2. General examination
3. Abdominal examination
4. Vaginal examination
5. Investigations including Complete blood picture (CBC), Kidney function tests, Liver functions tests (if indicated according to medical disorder)
6. Ultrasound:
It was carried out in the special care center of the ultrasound unit (Ain Shams University Maternity hospital).
Apparatus used 4-9 MHZ Mulifrequency transvaginal convex transducer (voluson E6, General Electtric Co. LTD).
For each patient, the endometrial myometrial interface was scanned in a systematic fashion using
o 2D Doppler ultrasound.
o 3 D U / S TUI
The following are the most important results of the present study:
In relation to Demographic data of study group, In relation to Demographic characteristics of the studied cases.
Mean±SD of Age (years) and BMI (kg/m2) was 55. 4±4. 1 and 26. 6±3. 2 respectively.
Median (1st−3rd IQ) of parity was 3.0 (4.0–4.0).
Majority ocases were postmenopausal (86.0%).
In relation to Clinical presentation of the studied cases.
Mean±SD of Duration of onset (years) was 2.3±1.1.
The most frequent presentation was vaginal beeding (80.0%), then Pelvic pain (48.0%).
Concerning Radiological findings of cervical stroma among the studied cases.
2D US (Invasion). Doppler (Feeding vessel), TUI (Coherent vessels) and CT (Invasion) were in 42.0%, 16.0%, 32.0% and 34.0% respectively.
Radiological findings of endometrium among the studied cases. 2D US (Invasion ≥50.0%), Doppler (Feeding vessel), TUI (Coherent vessels), TUI (Margin disruption) and CT (Invasion ≥50.0%) were in 38.0%, 18.0%, 34.0%, 34.0% and 38.0% respectively
In relation to Histopathology findings of the studied cases.
Mean±SD of Uterine length (cm), Uterine diameter (cm) and Tumor size (cm) was 13.9±2.4, 7.0±1.3 and 1.2±0.3 respectively.
Stroml invasion and Endometrium invasion ≥50.0% were in 32.0% and 36.0% respectively.
Almost all samples (96.0%) were Carcinoma, thr emaining (4.0%) were sarcoma.
Carcinoma subtypes were Endometroid (84.0%), Serous (8.0%) and Clear cell (4.0%).
Differentiation grades were Well (84.0%), moderate (12.0%) and poor (4.0%). FIGO stage was in the range from Ia to IIIc.
Statistically significant relationships were declared as the following:
No statistical significant difference according to cervical stroma invasion (histopathology) regarding demographic characteristics and clinical presentation.
2D US (Invasion ≥50.0%), Doppler (Feeding vessel), TUI (Coherent vessels), TUI (Margin disruption) and CT (Invasion ≥50.0%) were significantly more frequent in cases with positive cervical stroma invasion.
No statistical significant difference according to endometrium invasion (histopathology) regarding demographic characteristics and clinical presentation.