الفهرس 
Cardiovascular AnatomyOnly 14 pages are availabe for public view
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Abstract
Hypertrophic cardiomyopathy (HCM) is the most common genetic
cardiomyopathy, with a prevalence of 1:500 in the general population. Despite an
autosomal dominant mode of inheritance, phenotypic expression is highly
variable, and penetrance is age-dependent and incomplete.
Cardiac imaging in HCM remains the cornerstone for clinical diagnosis and
management guidance. For decades, conventional 2-D transthoracic
echocardiography (TTE) has been the preferred imaging modality for assessment
of HCM patients, due to its widespread availability and low cost. However, in
recent years, cardiac magnetic resonance (CMR) has shown increased penetrance
in clinical practice.
Thus. the aim of the current study is to identify the role and diagnostic
potential of cardiac magnetic resonance imaging to diagnose cardiomyopathy.
A cross section study was conducted in the period from October 2020 till
May 2022 at Radio Diagnosis Department, Menoufia University Hospitals. The
study involved 50 patients who had clinical suspicion of cardiomyopathy. They
were referred to by the cardiology department. The age of patients ranged from
39 to 84 years.
All patients were selected according to inclusion and exclusion criteria as
follow:
Inclusion criteria:
Both sexes patients who had clinical suspicion of cardiomyopathy on basis of
echocardiography, ECG changes.
Ages of patients ranged from 39 to 84 years.
Exclusion criteria:
Congenital heart disease.
Patients presenting with myocardial masses not related to cardiomyopathy.
Pericardial diseases and masses
Patients with allergy to gadolinium contrast media and history of renal
disease.
Other exclusion criteria were hemodynamic instability, atrial fibrillation,
contra-indications for MR imaging, claustrophobia, patients with pacemaker
or metal implants (cerebral aneurysmal clips).
Patients who have one or more of absolute or relative MRI contraindication
such as electronic, magnetic, mechanically activated implants and cochlear
implants, examinations markedly compromised by motion artifacts.