الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 228 |  |  |
| | | from | 228 | | |
Abstract
Muscle injuries can range from minor strains to severe tears, and they often result from strenuous physical activity or accidents. The body’s natural healing process typically involves inflammation, tissue repair and remodeling. However, this process is incomplete due to the development of scar tissue which is mechanically inferior to a normal muscle fibre and leave affected muscle susceptible to re-injury. Regenerative medicine is increasingly playing a vital role in muscle injury treatment, utilizing stem cells and platelet-rich plasma (PRP) to promote faster healing, tissue regeneration and improved outcomes.
The present work aimed to study the histological changes of induced skeletal muscle injury in adult rats and to compare the therapeutic potential of both bone marrow derived mesenchymal stem cells (BM-MSCs) and PRP in skeletal muscle regeneration through assessment of post treatment histological and biochemical changes. This study was conducted on fifty-two male Sprague Dawley rats, aged 6-8 weeks, weighing about 150- 200 g. Thirty-two rats served as the experimental groups while the other twenty rats were divided equally for obtainment of PRP and BM-MSCs respectively.The thirty-two experimental rats