الفهرس 
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Abstract
Summary
Tinnitus is the perception of a sound in the absence of a sound source. Tinnitus can have mild through to catastrophic effect on life-quality; it can disrupt hearing, attention and sleep, result in anxiety, and depression.
Vitamin B12 deficiency may cause demyelination of nerve cells in the cochlear nerve, which leads to hearing loss and tinnitus.
The aim of this study was to analyze the effect of Vitamin B12 deficiency on auditory brain stem response and otoacoustic emission in patients suffering from tinnitus.
This study included 30 patients with tinnitus and 30 controls.
All groups were subjected to: Medical history taking, Otological examination, Auditory Brain Stem Response, Transient evoked otoacoustic emissions and conventional brain MRI. Serum level of total vitamin B12 level was assessed.
Results revealed that:
1- Mean age of patients was 30.3 years and standard deviation of 6.9. There was no statistically significant difference between cases and controls regarding their age and sex.
2- There was a statistically significant difference between cases and controls regarding the level of Vitamin B12 level (P-value<0.001).
3- There was a statistically significant delay at wave I in cases than the controls in the right side while in the left side, wave I and III were statistically significant delay in cases than the controls.
4- There was a statistically significant higher amplitude of wave I in cases than the controls. There was insignificant difference between cases and controls regarding V/I amplitude ratio on both sides.
5- There was a statistically significant difference between cases and controls regarding the TEOAE (P-value<0.05).
6- That the most common loudness was at 35 dB and that most of cases had tinnitus at 6 kHz.
7- There was a statistically significant linear negative correlation between the tinnitus duration and wave (I) latency in Rt and Lt sides.
8- There was a statistically significant linear negative correlation between the tinnitus duration and wave (I) amplitude at both ears. There was a significant linear positive correlation between the V/I ratio and the tinnitus duration at both ears in all patients.
9- There was no statistically significant linear correlation between vitamin B12 level and the ABR latency or amplitude.
10- There was a statistically lower level of vitamin B12 in cases with refer TEOAE than pass in both sides.