الفهرس 
Leptin andghrelin response toaerobic exercises in post-colectomy patients
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Abstract
Patientspostcolectomy experienceasubstantialdeclineinfitnessleveland qualityoflife.Obesityisoneofthemostimportantriskfactorsforcolorectalcancerand studiesshow that aerobicexercises and weightlossprogramwillresultin reduction of leptinandincreaseofghrelininpatientswithcolorectalcancer.Objectives:Toinvestigate plasma leptinandghrelinconcentrationsinmalepatientswithcolorectalcancerpostcolectomyafter
8 weeks of aerobic exercise and after a week of detraining. Patients, Materials and Methods: A cross-sectional observational study was conducted on thirty menpatients selectedfromSurgeryDepartmentatElMiniaUniversity Hospital(Egypt).Theywere assignedrandomly intotwoequalgroupsinnumber,theiragerangedfrom50-60years. Patientswereevaluatedby Rockportwalkingtestusing(treadmill),Fazziniweightscaleand fastingbloodplasmatestusingEnzymeLinkedImmunosorbentAssay(ELISAkit)before andafterthestudy.Thestudygroup(A)receivedaerobictrainingfor8weeksas3sessions
/weekeachsessionlastsfor45minutesandcontrolgroup(B)wereonlyadvisedabout healthylifestyle.Results:TheresultsshowedthatVO2peakwassignificantly increasedand heartratewassignificantlydecreasedinthetraininggroupcomparedtothecontrolgroup(P
<0.05).Ghrelinconcentrationwasincreasedsignificantly inthetraininggroupcomparedto thecontrolgroup(P<0.05),whileplasmaleptinhormonedidnotchangesignificantly after trainingfor both groups.
Conclusion: Thestudyconcluded thataerobictrainingincreasesghrelin hormone levelsVO2 peakafter8weeksofaerobicexerciseandaweekofdetraining however, plasmaleptindose not affected bythis protocol in malepatients with colorectalcancer.