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العنوان
Conventional Cytology Using Ayr’s Spatula Technique versus Liquid Based Cytology in Cervical Cancer Screening; A Prospective Self Control Clinical Trial/
المؤلف
Morgan,Heba Allah Alaa Eldin Yasin
هيئة الاعداد
باحث / هبة الله علاء الدين ياسين مرجان
مشرف / هشام محمود محمد حرب
مشرف / مروة عبد المولى الجندي
تاريخ النشر
2023
عدد الصفحات
133.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - Obstetrics & Gynaecology
الفهرس
Only 14 pages are availabe for public view

from 147

from 147

Abstract

Background: Cancer cervix is one of the most common forms of genital malignancy among women. The conventional cervical smear technique has inherent screening problems and interpretation errors.
Objective: The objective is to assess the efficacy of liquid-based cytology as a method for cytological screening in comparison to conventional Pap smear technique for screening of cervical cancer.
Methods: This study was conducted on a total of 30 women who attended ASUMH ECDU for cervical smear. During this study, 45 patients were assessed for eligibility and 30 patients were included in the study. Of all eligible patients, 8 patients were excluded from the study based on the inclusion criteria and 7 patients refused to participate in of the study.
Results: Sample adequacy was more frequent in LBC samples than in Pap smear samples. The difference between Pap smear and LBC was wide, the agreement between them was non-significant indicating no agreement between Pap smear and LBC regarding Sample adequacy. Mucous was detected only in Pap smear samples (16.7%) and inflammatory cells were more detected in LBC samples than in Pap smear samples (50% versus 23.3%) respectively with no blood detected in the samples.
Conclusion: Sample adequacy showed no statistically significance difference between Pap smear and LBC and the liquid-based cytology was introduced as an alternate technique to some extent produces monolayer smears which are easier for interpretation as there is no overlapping or clumping and cells with atypia are not obscured by other of cells or background (inflammation, blood, mucus etc). However, CPS still remains a better option in the context of countries with a resource-poor setting but with trained personnel for Pap screening.