الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 152 |  |  |
| | | from | 152 | | |
Abstract
Oxygen supplementation is often used universally to counteract hypoxemia in a hospital setting. However, studies have demonstrated that inattentiveness to SpO2 levels while providing oxygenation therapy may lead to periods of hyperoxemia and tissue hyperoxia, there is a clinical trend toward reducing the extent and duration of oxygen exposure to avoid hyperoxia while minimizing detrimental effects attributable to insufficient oxygen saturations. (William et al., 2012)
The aim of this current study was to systematically review the efficacy and safety of conservative versus liberal oxygen therapy, and to measure the caliber of trachea and main bronchi at the start and end of treatment by oxygen therapy to show if it has an effect on AP and transverse dimensions of trachea and main bronchi
The current study is a prospective study that was conducted on 72 patients with respiratory failure type 1 in department of Chest Diseases in Ain Shams University and Specialized Hospital and Abbaseya Chest Hospital. They were enrolled consecutively according to a schedule for wards and ICU visits. group A is 36 patients received liberal oxygen and group B is 36 patients received conservative oxygen.
Form the present study it’s concluded that:
There was statistically significant increase in the percentage of patients with arrhythmia in group B (33.3%) than group A (8.3%) with p-value = 0.009
As regard infections, (25%) had hospital acquired infection in group A, and (16.7%) in group B with no significant difference and p-value = 0.384. But the percentage of patients with hospital acquired pneumonia was found significantly higher in group A (16.7%) than group B (2.8%) with p-value 0.047.
The length of hospital stay was found statically significant higher in group A (12.44 ±4.11) than group B (8.53 ± 3.97) with p-value <0.001.
As regard mechanical ventilation, this study also shows no statically significant difference between group A (0-13) and group B (0-10) as regard mechanical ventilation free days with p value = 0.609. And it shows also that no difference in group A (13.9%) and group B (16.7%) in regard trends to lower use of mandatory MV mode, which might indicate earlier attempts to wean patients with p value = 0.743%.
No statistically significant difference found between both groups as regard vasopressor dose, ARDS as new complication, new organ dysfunction and ICU mortality, hospital mortality and 30day mortality.
Regarding the difference between AP and lateral diameters of both trachea and main bronchi before and after oxygen therapy by CT assessment, there was no statistically significant difference found between both groups.