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العنوان
Preparation of hybrid filled chitosan nanocomposites for drug delivery and structural correlation with electrical conductivity /
المؤلف
El-Hanish, Samar Ebrahim Mohamed.
هيئة الاعداد
باحث / سمر ابراهيم محمد الحنش
مشرف / مجدى يوسف عبد العال
مشرف / داليا مختار عياد
مشرف / عمرو محمد عبدالغني
مناقش / أشرف عبد الحميد الشهاوى
مناقش / محمد حسن عبدالرحمن شريف
الموضوع
Chemistry. Nanocomposites (Materials).
تاريخ النشر
2023.
عدد الصفحات
191 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة المنصورة - كلية العلوم - Chemistry Department
الفهرس
Only 14 pages are availabe for public view

from 191

from 191

Abstract

Introduction: Diabetes mellitus (DM) is a metabolic disease characterized by the presence of hyperglycemia secondary to insulin secretion deficit or absence and/or to a receptor or post-receptor defect in insulin action, with impaired insulin secretion and/or biological action. Bariatric surgery has been recognized as one of the most effective treatments for obesity. Some authors termed bariatric surgery as metabolic surgeries induce long-term remission of type 2 diabetes mellitus (T2DM) and dramatically improve other metabolic abnormalities, such as hyperlipidemia and hypertension, independent of the patient’s weight. Patients & Methods: This interventional randomized interventional study included 32 subjects with BMI ≥35kg/m2 with Type II diabetes mellitus. They were randomly allocated into two equal groups; group A that included 16 patients who underwent LSG and group B included that included 16 patients who underwent SASI procedure. Results: Follow up visits were scheduled for all cases at 3, 6, 9, and 12 months after the procedure with assessment of clinical and laboratory outcomes including mainly the percent of excessive weight loss, improvement of diabetic parameters, detection of complications following surgery, a reduction in dyslipidemia and assessment of nutritional deficiencies. Discussion: There was a statistically significant decrease in the fasting blood glucose, postprandial blood glucose, random blood glucose and glycosylated hemoglobin in the two study groups long the duration of follow up with no statistically significant difference between the two groups. Conclusion: No technique revealed statistically significant superiority over the other, however the LSG was associated with shorter operative time and SASI bypass was associated with less development of De Novo GERD.