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Abstract
Poor responders were classified with at least two of the three following criteria: (I) advanced maternal age or any other risk factor for POR; (II) a previous; and (III) an abnormal ovarian reserve test (ORT):, as described by the Bologna criteria. The aim was to evaluate the role of DHEA supplementation in improvement of IVF outcome. 100 patients attending Kasr El Ainy IVF unit and classified as poor responders according to ESHRE consensus 2011 were included. All the patients were subjected to GnRh short agonist. group A patients will not receive (n=50) DHEA (control group). group B patients (n=50) will receive DHEA in a dose of 25 mg t.i.d. for 3 months prior to their second ICSI/embryo transfer cycle. Our study found that there were no statistical differences between DHEA group and control group regarding ovarian reserve markers nor pregnancy rate but may improve quality of oocytes and transferred embryos