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Abstract Reactive protein in type 2 diabetic patients with retinopathy if we use the funds photograph to classify diabetic patients with retinopathy to nonproliferative diabetic retinopathy and proliferative diabetic retinopathy or be used as one group. Subject 80 subjects divided to T2DM (n=30), type 2 diabetic patients with retinopathy (n=30) divided to (n=15) proliferative and (n=15) non-proliferative and healthy controls (n=20). In this cross-sectional study, diabetic retinopathy status was assessed by fundus examination. Results When we compared the levels of NSE or hsCRP levels between the studied groups showed statistically significant elevation (P<0.0001 separately) and when combined the NPDR and PDR as one group showed also highly significant elevation (P<0.0001), ROC curve used for determination the AUC at the best cut off. Conclusion NSE and hsCRP can be used as potential biomarkers for the detection of type2 diabetic patients with retinopathy |