الفهرس 
Study of antibiotics sensitivity and resistance genes of acinetobacter baumannii in upper Egypt
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Abstract
Acinetobacter baumannii growing resistance is a worldwide problem. The incurable strains of A. baumannii endanger the lives of millions of hospitalized patients every year. Continuous study of its resistance pattern is a must to control its devastating effect on the quality of medical treatment. from January 2014 to May 2015, a total of 1021 isolates were collected from different wards of Alazhar and Assuit university hospitals, Assuit government. A number of 69 (6.76%) A. baumannii isolates were identified using both biochemical and PCR reactions. The PCR detected the presence of blaOXA51 which is a DNA marker unique to A. baumannii different strains. The antimicrobial susceptibility pattern of the 69 A. baumannii isolates, determined by kirby bauer disc diffusion method, showed high resistance rates against cefpime 94.2% (65 / 69), Cefotaxime 92.75% (64), pipracillin 91.3% (63), ceftazidime 89.85% (62), Ceftriaxone 88.40% (61),Ciprofloxacin 84.05% (58),Tobramycin 82.60% (57), Tazopactam 81.16% (56), Sulbactam 79.71% (55), imipenem and meropenem 76.81% (53), sulphamethoxazole 75.36% (52) amikacin and gatifloxacin 73.91% (51 / 69), tigecycline 71% (49). In addition to 2 pan drug isolates recorded as resistant to all tested antibiotics (2.90%). On the other hand, colistin was the most effective antibiotic with a susceptibility of 92.75% followed by Doxycycline with 49.27%