الفهرس 
Obsessive Compulsive Symptoms in Bipolar Disorder: OverviewOnly 14 pages are availabe for public view
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Abstract
Bipolar disorder (BD) is a disabling and chronic neuropsychiatric disorder, which is characterized by a complex illness presentation and episode recurrence; it includes a series of signs and symptoms, the defining characteristic being pathological mood changes. BD is highly comorbid with psychiatric and medical disorders. Among the first, the association between BD and OCD has been widely described.
The current study aimed to assess the occurrence of OCS in patients with BD, to study the clinical profile of OCS in BD and to compare OCS profile in manic episodes and in depressive episodes of BD.
One-hundred BD patients were recruited according to DSM-4, they were classified into two groups: bipolar depression and bipolar mania. Full personal history recording was performed then, SCID-I was conducted to diagnose BD and the exclusion of other psychiatric disorders. Y-BOCS was used to diagnose OCD and assess severity of it and finally, SCID-II was used to diagnose an axis II diagnosis.
Of the included patients, only 30% had OC symptoms comorbid with BD. Bipolar-OCD patients (30 patients) were 22 males and 8 females with mean age 35.5±10.5 years. Twelve patients were single, 12 married and 6 divorced. On the other hand, bipolar without OCD patients were 53 males and 17 females with mean age 38.4±10.1 years. Twenty-nine patients were single, 30 were married ,10 divorced and 1 widow. Family history of psychiatric disorders statistically was significantly more frequent in cases presented with bipolar-OCD patients.
Regarding clinical data of BD among the studied cases, mean age of onset of disease was 24.3±8.0 while mean duration of disease was 13.1±8.8 years. Eighty percent of patients were on anti-psychotic drugs plus mood stabilizers. Past history of hospitalization statistically was significantly more frequent in cases with mania. There were no statistically significant differences between mania and depression regarding demographic data.
Y-BOCS assessment revealed that Patients with comorbid OCD were more like to occur during depressive episode representing 73.3% of cases, symmetry was the most frequent obsession type representing 63.3% of cases while checking was the most frequent compulsive type representing 73.3% of cases. Majority of cases (60%) had mild symptoms, in addition mean obsession score was 7.8±2.9, the mean compulsive score was 7.8±3.4, and the mean Y-BOCS scale was 15.6±5.9. No statistically significant differences between manic and depressive episodes of bipolar disorder regarding obsession score, compulsive score, and total Yale-Brown Obsessive-compulsive score.