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العنوان
Validated chromatographic methods for studying the effect of lycopene on the pharmacokinetics of some drugs /
الناشر
Reem Baha Aldeen Youssef,
المؤلف
Reem Baha Aldeen Youssef
هيئة الاعداد
باحث / Reem Baha Aldeen Youssef
مشرف / Asmaa Ahmed Elzaher
مشرف / Marwa Ahmed Fouad
مناقش / Asmaa Ahmed Elzaher
تاريخ النشر
2018
عدد الصفحات
122 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
العلوم الصيدلية
تاريخ الإجازة
24/4/2018
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 140

from 140

Abstract

This thesis is concerned with studying the effect of lycopene on the pharmacokinetics of some drugs by development of simple and accurate RP- HPLC methods for the analysis of paracetamol, chorzoxazone , and theophylline in rats. The thesis consists of the following sections: Section I: Introduction It includes: I. A review about the pharmacokinetics, food {u2013}drug interaction, and investigated drugs II. Literature review about the reported methods for the quantitative determination of the drugs under investigation in human plasma and ratsIII. Aim and basis of the work: this section includes the aim of this work and the basis on which the work had been done. Section II: Experimental part and Discussion This section is divided into three parts: Part I: HPLC method for studying the effect of lycopene on pharmacokinetics of paracetamol in rats Part II: HPLC method for studying the effect of lycopene on pharmacokinetics of chlorzoxazone in rats Part III: HPLC method for studying the effect of lycopene on pharmacokinetics of theophylline in rats Section III: English Summary. Section IV: References, this section contains 151 references. Section V: Arabic Summary