Search In this Thesis
   Search In this Thesis  
العنوان
Prognostic Value of QRS Complex Fragmentation in Patients with Acute Anterior STEMI undergoing Primary PCI During in-Hospital Stay \
المؤلف
Alessawy, Mahmoud Gamal Elgaly.
هيئة الاعداد
باحث / محمود جمال الجالى العيسوى
مشرف / أدهم أحمد عبد التواب
مشرف / محمد مصطفى فاروق
مناقش / أدهم أحمد عبد التواب
تاريخ النشر
2022.
عدد الصفحات
129 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية الطب - أمراض القلب والأوعية الدموية
الفهرس
Only 14 pages are availabe for public view

from 129

from 129

Abstract

Primary percutaneous coronary intervention (PCI) as a type of coronary reperfusion therapy may lead to recanalization and improved myocardial reperfusion in patients with ST elevation myocardial infarction (STEMI).
The presence of a fragmented QRS (fQRS) complex including narrow or wide QRS complex, which corresponds to the depolarization of the right and left ventricles of the human heart is frequently recorded following surface electrocardiograms (ECGs). Previous studies have identified that fQRS complex on surface ECG is a predictor of adverse cardiovascular events, including cardiac mortality and heart failure.
The aim of our study is sought to investigate the prevelance of fQRS complex in ECG of patients admitted with acute anterior STEMI undergoing primary PCI and its short-term prognostic value during hospital stay.
In the current study, 156 consecutive patients with anterior STEMI being treated with primary PCI between July 2021 and March 2022 were enrolled. Patients were included in the study if they presented with symptoms that were identified typically as typical chest pain lasting for more than 20 min; had ST-segment elevation ≥1 mm in two contiguous electrocardiographic and had undergone primary PCI including balloon angioplasty, thrombus aspira tion and/or stent implantation.
The patients were divided into two groups based on the presence or absence of fQRS following ECG assessment. Presence of fQRS was defined as fQRS(+) (n=58) group (A), and absence of fQRS was defined as fQRS( ) (n=98) group (B). Following primary PCI and follow up, patients were divided into four another subgroups based on the following: New onset of fQRS(n=10),. Named subgroup B 1, Resolution of fQRS(n=16), Named subgroup A 1, Persistence of fQRS (n=42) Named subgroup A 2, Absence of fQRS (n=88) Named subgroup B 2
Our results study showed that, in patients with a diagnosis of anterior STEMI, the presence of fQRS at admission ECG is associated with the development of MACE at short-term follow-up and higher mortality. In addition, fQRS was the strongest predictor of MACE in patients with acute MI after adjustment for the risk factors of ischemic heart disease.