الفهرس 
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Abstract
This is a prospective study carried out on 40 eyes of 40 patients in order to study the changes in anterior segment parameters after pars plana vitrectomy surgery in diabetic patients. There were 19 males and 21 females and the average age was 64.7. 90% of the cases were phakic and 10% only were pseudophakic. All patients were NIDDM and we only included patients who had uneventful pars plana vitrectomy.
In the current series, we evaluated ECD and ECL using non-contact Specular microscopy and we evaluated ACA using non contact AS-OCT. We also used non contact Pentacam in order to evaluate ACD, ACV, CCT and Astigmatism.
There was no significant statistical difference between pre-operative and post-operative IOP ranging between 7 and 25 mmHg with the highest fluctuation during week 1.
Regarding the changes in corneal endothelium, there was a statistically significant decrease in endothelial cell density as ECL steadily increased after the surgery although the surgery included vitrectomy without any combined cataract surgeries. This ECL was not showing any correlation with age nor gender.
Corneal astigmatism was studied using Pentacam and observation of K readings showed insignificant fluctuation during the postoperative visits and there was no change in axis of astigmatism as well.
We also used Pentacam Schimpflug images to evaluate the central corneal thickness after PPV. The study showed that there was statistically significant - although clinically insignificant – changes in CCT during 1st and 2nd month of the postoperative period. On the last visit, CCT returned back to the preoperative value.
Regarding the depth of anterior chamber, there was significant postoperative increase after 1 week which gradually decreased afterwards reaching closer to its preoperative value after 3 months. The statistical analysis of ACD confirmed statistically significant increase in all visits though.
The mean preoperative ACV was 153+/-18. The mean ACV after 1 week insignificantly increased to 155+/-19 which significantly increased further in the following 2 visits to 156+/-19. It even showed further increase to 158+/-19 in the last visit. All changes in ACV were statistically significant except the 1 week’s visit.
To evaluate the angle of the anterior chamber, we used AS-OCT but also we collected data for same patients from their Pentacam examination. We used AOD500 parameter as an indication of ACA. We calculated both nasal and temporal ACA which always showed that nasal ACA values were always lower than temporal ones. Using AS-OCT, the calculation of ACA was stable in all visits with insignificant fluctuations. The Pentacam assessment of ACA did show same values suggesting no difference between both investigations.