الفهرس 
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Abstract
Background : Stroke is a leading cause of major adult disability, and aphasia is one of the most common consequences of stroke. Aim : The current study aimed to correlate the severity of different types of post stroke aphasia with the affected brain areas in Arabic speaking Egyptian patients and to identify the changes that occur clinically and by advanced MR imaging of the affected brain areas pre versus post language therapy. Patients and Methods : We identified changes that occur by diffusion tensor imaging (DTI) of the affected brain areas in right handed patients (n=27) compared to healthy brain areas in control (n=27), age and sex matched healthy individuals. In addition to that, the study was conducted to identify the effect of language therapy on both aphasia scoring and DTI imaging. We compared the (9) patients who completed to language therapy with (9) patients without language therapy with follow-up after six months. Results: The mean FA of AF and SLF in patients with aphasia were significantly lower than control. The disintegration of the neural tract was associated with decrease FA. The mean MD value of AF and SLF in patients with aphasia were significantly higher than the mean MD value in control .The volume of AF and SLF tracts were decreased on DTI which could be used as follow up DTI parameters in stroke patients. The nine Patients who received Schuell’s stimulation for language therapy for six months with daily home counseling and medical treatment showed a significant improvement in MASAT score. Conclusion : We concluded that the role of neuroimaging parameters, including FA and MD of AF and SLF as well as tract volume could be used in detection of changes in language areas in patients with post stroke aphasia. Also, neuroimaging parameters could be correlated with the patient’s clinical data. These findings were associated with the severity of aphasia during the early, sub-acute and chronic phases of stroke.