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العنوان
Clinical and Laboratory characteristics of Psoriatic Arthritis in a Cohort of Egyptian Patients \
المؤلف
Ghalwash, Rofida Abdellatif Ibrahim.
هيئة الاعداد
باحث / روفيدة عبدالطيف إبراهيم غلوش
مشرف / عادل محمود علي السيد
مشرف / نوران أسامة أحمد العزيزي
مشرف / داليا عبدالحميد الشربيني
تاريخ النشر
2021.
عدد الصفحات
212 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الروماتيزم
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - الأمراض الروماتيزمية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Aim of the work: To detect the clinical and laboratory characteristics of psoriatic arthritis (PsA) in sample of Egyptian population.
Patients and methods: 100 PsA patients were subjected to full medical history, full clinical, musculoskeletal and dermatological examination, routine laboratory investigations and assessment of disease severity.
Results: Among 100 PsA patients, 79 females and 21 males. The mean age was 44.4 ± 12.9 years. 21% of patients had hypertension, 11% had diabetes and 4% hepatitis C-virus. 14% had family history of other rheumatologic disease. 66% of patients experienced psoriasis onset with mean latency; 11.6 ± 8.2 years, 20% had dual onset of both diseases and 10% experienced PsA first with mean latency 3.6 ± 3.5 years. 86% of the patients had enthesitis, 41% had dactylitis, 39% had axial affection and 18% of patients had uveitis. 90% of patients had current psoriasis and 89% of them had current nail lesion. The most common drug was methotrexate. 38% of patients had axial spondyloarthritis, 33% had symmetric polyarthritis, 26% had asymmetric oligoarthritis, and 3% had predominant distal inter-phalangeal (DIP) involvement. The mean value for serum hemoglobin was 12.1 ± 8.21.6 g/dl, platelets; 278.4 ± 90.3 x103/mm3, the white blood cells 7.2 ± 2.2 x103/mm3, C-reactive protein was 10.9 ± 10.1 mg/dl and erythrocyte sedimentation rate was 49.3 ± 27.5 mm/1st hr. 92% of patients were negative for rheumatoid factor.
Conclusion: Among the cohort of Egyptian patients, most had axial spondyloarthritis, followed by symmetric polyarthritis and asymmetric oligoarthritis. The least frequent was predominant DIP involvement. The onset of psoriasis precedes arthritis and methotrexate was the most common therapy. _ 2021 THE AUTHORS. Publishing services by ELSEVIER B.V. on behalf of The Egyptian Society of Rheumatic Diseases. This is an open access article under the CC BY-NC-ND license