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العنوان
Cardiac Troponin T Level in Pediatric Patients with Respiratory Distress /
المؤلف
Mossad, Hania Naguib.
هيئة الاعداد
باحث / هانيا نجيب مسعد
مشرف / ليلى عبد الغفار حجازي
مشرف / سالى رأفت إسحق
مشرف / نانسى سمير وهبه
تاريخ النشر
2019.
عدد الصفحات
134p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - طب الاطفال.
الفهرس
Only 14 pages are availabe for public view

from 134

from 134

Abstract

SUMMARY
R
espiratory distress is one of the most common reasons for pediatric emergency department visits and hospitalizations.
Respiratory distress, due to any cause, stresses the heart by increasing myocardial oxygen demand, this imbalance in myocardial oxygen supply and demand may cause of elevated cardiac Troponin T.
Cardiac troponin T (cTnT) is a subunit of a thin filament of the contractile apparatus of the myocardium. It is a cardiospecific and highly sensitive marker for myocardial damage in children.
This case control study was conducted on 50 children (62% males, 38% females) with respiratory distress (52% of them had pneumonia), from the pediatric emergency room and inpatient wards of the children’s hospital, Ain Shams University Hospitals. They were compared to 50 age and sex matched children as control for Troponin T values.
The aim of the current study was to study cardiac complications and injury with respiratory distress and correlate it with the severity of the respiratory distress through screening for cardiac affection by measuring Troponin T level by ELISA.
All patients were subjected to detailed history, thorough clinical examination, chest x-ray, laboratory investigations included complete blood count, C-reactive protein and troponin T level by ELISA.
In the current study, Patients’ age ranged from 1 month to 144 months old with mean age 61.08 months.
In our studied patients group: 100% were tachypneic, 42% had wheezes, 40% had subcostal retraction and 46% refuse feeding.
These signs were significantly higher in patients with severe respiratory distress than in patients with moderate respiratory distress.
Serum Troponin T levels in studied patients group were all above reference value 0.01 ng /ml ranged with mean (0.02578 ± 0.01290ng/ml), there was statistically significant difference found between control group and diseased group as regards troponin T value.
In our studied patients group, there was positive Correlation between cardiac Troponin T level and PRESS score in patients with respiratory distress.
As regards cardiac manifestations, in our study, (34%) of the patients were tachycardic and there was a highly significant correlation between cardiac troponin T and heart rate.