الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
The automated gas control (AGC) system of Maquet FLOW-i anesthesia machine allows the user to choose the speed by which the desired end-tidal anesthetic concentration is reached. We compared two isoflurane wash in speeds (speed 2 and 9) regarding the hemodynamic changes occurring in the post induction period. We studied 120 ASA II and III and geriatric surgical patients. Immediately after intravenous anesthetic induction and securing the airway, the AGC was activated using either speed 2 or speed 9 in the speed 2 group (n=60) or speed 9 group (n=60), respectively. The study period extended for 20 minutes after activating AGC. PIH was defined as either mild (DROP by˃20% from baseline) or severe hypotension (DROP by ˃40% from baseline with administration of ephedrine). The following parameters were compared among the two groups: age, sex, height, weight, heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, total ephedrine dose and incidence of post-induction hypotension (PIH). Patient demographics did not differ among groups. Heart rate did not show a statistically significant difference between both groups. Incidence of mild hypotension was 98.3% in speed 9 group and 88.3% in speed 2 group (P<0.02). Incidence of severe hypotension was 70% and 21.7% in speed 9 and speed 2, respectively (P<0.001). The results of this study show that using a slow isoflurane wash in speed decreases the incidence of severe PIH in patients who are at risk for hypotension after induction of anesthesia.