الفهرس 
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Abstract
Barrett’s esophagus is a condition which predisposes towards development of dysplasia and finally towards esophageal adenocarcinoma, a highly lethal tumour which has been increasing in incidence over the past three decades.
Although BE is the single best identified risk factor for the development of esophageal adenocarcinoma, yet the overwhelming majority of Barrett’s patients will never develop this cancer.
As the prevalence of dysplasia and esophageal adenocarcinoma increases, research has discovered epidemiologic, endoscopic and pathologic factors that may help determine risk for neoplastic progression. It is hoped that algorithms can be developed to risk stratify patients in the future to tailor optimal therapy and intervention to prevent the development of dysplasia and hence adenocarcinoma.
There have been also significant advances in the field of BE not only in diagnosis, but also in the different endoscopic imaging and therapeutic modalities.
Currently, surveillance forms the mainstay of BE management with surveillance intervals varying depending on the grade of dysplasia.
The aim of this study was to evaluate the incidence of dysplasia in patients with BE regarding risk factors such as gender, smoking, obesity, patient’s age, duration of reflux, treatment received, associated disease as DM and esophageal histopathology.
The study was conducted on 30 patients previously diagnosed with BE. The patients were selected according to some inclusion criteria such as being diagnosed by upper GI endoscopy and a biopsy was taken. Patients with history of previous anti-reflux surgery were excluded.
A strong correlation was found between the incidence of dysplasia and male gender, mean age 58.17 years, smoking, DM, hiatus hernia and esophagitis.
The incidence of dysplasia in patients with Barret’s esophagus was found to be 40%. from the patients that developed dysplasia on top of BE, 66.7% had esophagitis, 60% were males, 40% were diabetic and 40% were smokers, with mean age 58.17 years and mean of reflux duration 2.09 years.