الفهرس 
LiiverOnly 14 pages are availabe for public view
 |  | from | 173 |  |  |
| | | from | 173 | | |
Abstract
Summary
The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis and production of biochemicals necessary for digestion. This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. Hepatitis B virus causes inflammation of liver. The virus spreads through contact with infected body fluids, such as through sexual intercourse, open cuts or scratches, or from mother to baby at birth. The most common symptoms of acute hepatitis B are loss of appetite, nausea, generally feeling poorly, and pain or tenderness in the right upper part of the abdomen (where the liver is located).
Goals of therapy: 1- Prevent progression of fibrosis and development of cirrhosis or HCC by suppressing HBV replication. 2- Seroconversion from HBeAgt to anti-HBe and establishment of effective immune control. 3- Suppression of HBV DNA, however, therapy does not eradicate HBV in hepatocytes. The hepatitis B vaccine (HBV or HePB) is an injection that prevents serious disease caused by the hepatitis B virus. The hepatitis B vaccine consists of a small protein from the hepatitis B surface antigen (HBsAg). After vaccination with HBsAg as a foreign agent, it produces antibodies that attach to remain in the blood. Later, the child becomes infected with the virus. The protein stimulates the immune system to work antibodies and destroy the virus and prevent the disease. Hepatitis B vaccination is contraindicated for persons with a history of hypersensitivity to yeast or to any vaccine component. Pregnancy is not a contraindication to vaccination. Limited data indicate
no apparent risk for adverse events to developing fetuses when hepatitis B is administered to pregnant women. Hepatitis B vaccination strongly protected against infection for at least 15 years in all age groups. Antibody levels decreased the most among immunized at 4 years of age or younger. Absence of anti hepatitis B surface antibody after vaccination does not necessarily mean absence of immune response. All nonimmune dental health care workers should receive immunization with recombinant hepatitis B vaccine